Supervisor
Prof. Laura Formentini
Laura Formentini is a Professor of Biochemistry at UAM, Coordinator of the Unit, coordinator of the TRAIN@CBM PhD School, and Principal Investigator at the CBM (UAM-CSIC). She leads the Translational Energy Metabolism (TEM) Group at UAM and at the Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12). She holds a PhD in Pharmacology from the Università di Firenze (cum laude, 2010). Her research is focused on the role of mitochondrial metabolism in cellular homeostasis, metabolic disease, and ageing, with publications in leading journals including Nature Metabolism, EMBO Journal, Nature Communications, and Molecular Cell. She has been PI of competitive national and European projects over the last five years and is currently supervising four doctoral theses, with seven PhD theses successfully completed to date. Her extensive experience in research, teaching, international collaborations, and doctoral training provides an excellent environment for high-level scientific training and career development within the MSCA program.
Selected publications
Morin E. et al. | EMito-Metrix enables automated evaluation of mitochondrial morphology across species.
Nat. Metab. (2025), DOI: 10.1038/s42255-025-01400-z
Herrero Martín J.C. et al. | An ETFDH-driven metabolon supports OXPHOS efficiency in skeletal muscle by regulating coenzyme Q homeostasis.
Nat. Metab. (2024), DOI: 10.1038/s42255-023-00956-y
Sanchez-Gonzalez C. et al. | Dysfunctional muscle oxidative phosphorylation shunts BCAA catabolism onto lipogenesis in skeletal muscle
EMBO J. (2020), DOI: 10.15252/embj.2019103812
Nuevo-Tapioles C. et al. | Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth
Nat. Commun. (2020), DOI: 10.1038/s41467-020-17384-1
Formentini L. et al. | Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance
Diabetologia (2017), DOI: 10.1007/s00125-017-4379-z
Formentini L. et al. | Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization
Cell Rep. (2017), DOI: 10.1016/j.celrep.2017.04.036
Research group website: CMB Severo Ochoa